Activation of phosphatidylinositol 3-kinase by membrane localization of p110alpha predisposes mammary glands to neoplastic transformation. [electronic resource]
Producer: 20090116Description: 9643-53 p. digitalISSN:- 1538-7445
- Animals
- Cell Line, Tumor
- Cell Membrane -- enzymology
- Cell Transformation, Neoplastic -- genetics
- Class I Phosphatidylinositol 3-Kinases
- Cyclin-Dependent Kinase 4 -- biosynthesis
- Enzyme Activation
- Female
- Genetic Predisposition to Disease
- Mammary Glands, Animal -- enzymology
- Mammary Neoplasms, Experimental -- enzymology
- Mammary Tumor Virus, Mouse -- genetics
- Mice
- Mice, Transgenic
- Phenotype
- Phosphatidylinositol 3-Kinases -- genetics
- Promoter Regions, Genetic
- Retinoblastoma Protein -- genetics
- Transgenes
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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