Delivery of Interferon-gamma by an adenovirus vector blocks herpes simplex virus Type 1 reactivation in vitro and in vivo independent of RNase L and double-stranded RNA-dependent protein kinase pathways. [electronic resource]
Producer: 20090402Description: 39-43 p. digitalISSN:- 0165-5728
- Analysis of Variance
- Animals
- Cytokines -- metabolism
- Endoribonucleases -- deficiency
- Enzyme-Linked Immunosorbent Assay -- methods
- Female
- Genetic Vectors -- administration & dosage
- Herpes Simplex -- genetics
- Herpesvirus 1, Human -- physiology
- Interferon-beta -- genetics
- Interferon-gamma -- administration & dosage
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Time Factors
- Transduction, Genetic -- methods
- Ultraviolet Rays
- Virus Activation -- physiology
- eIF-2 Kinase -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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