Oncogenic K-Ras regulates proliferation and cell junctions in lung epithelial cells through induction of cyclooxygenase-2 and activation of metalloproteinase-9. [electronic resource]
Producer: 20090410Description: 791-800 p. digitalISSN:- 1939-4586
- Amino Acid Sequence
- Animals
- Cadherins -- chemistry
- Carcinoma, Non-Small-Cell Lung -- enzymology
- Cell Culture Techniques
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Shape -- drug effects
- Cyclooxygenase 2 -- biosynthesis
- Cyclooxygenase Inhibitors -- pharmacology
- Electric Impedance
- Enzyme Activation -- drug effects
- Enzyme Induction -- drug effects
- Epithelial Cells -- cytology
- Humans
- Intercellular Junctions -- drug effects
- Lung -- cytology
- Matrix Metalloproteinase 9 -- metabolism
- Molecular Sequence Data
- Protein Stability -- drug effects
- Proto-Oncogene Proteins p21(ras) -- metabolism
- Rats
- Signal Transduction -- drug effects
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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