PKCalpha activation downregulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo. [electronic resource]
Producer: 20090916Description: 54-63 p. digitalISSN:- 1555-8576
- 4-Butyrolactone -- analogs & derivatives
- Androgens -- pharmacology
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- genetics
- Cell Division -- drug effects
- Cell Line, Tumor
- DNA-Binding Proteins -- genetics
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- Humans
- Kinetics
- Male
- Prostatic Neoplasms -- enzymology
- Protein Kinase C-alpha -- metabolism
- Protein Serine-Threonine Kinases -- genetics
- Tetradecanoylphorbol Acetate -- pharmacology
- Tumor Suppressor Proteins -- genetics
- Valerates -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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