Rho-kinase inhibitors decrease TGF-beta-stimulated VEGF synthesis through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts. [electronic resource]
Producer: 20090203Description: 196-203 p. digitalISSN:- 1873-2968
- 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- analogs & derivatives
- 3T3 Cells
- Animals
- Animals, Newborn
- Enzyme Inhibitors -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Mice
- Myosin-Light-Chain Kinase -- metabolism
- Myosin-Light-Chain Phosphatase
- Osteoblasts -- drug effects
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Skull -- cytology
- Transforming Growth Factor beta -- pharmacology
- Vascular Endothelial Growth Factor A -- biosynthesis
- p38 Mitogen-Activated Protein Kinases -- metabolism
- rho-Associated Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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