Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. [electronic resource]
Producer: 20090107Description: 3530-40 p. digitalISSN:- 0004-3591
- 8-Bromo Cyclic Adenosine Monophosphate -- pharmacology
- Aged
- Antibodies -- pharmacology
- Carbazoles
- Cells, Cultured
- Chondrocytes -- drug effects
- Colforsin -- pharmacology
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- antagonists & inhibitors
- Enzyme-Linked Immunosorbent Assay
- Humans
- Interleukin-1beta -- pharmacology
- Isoquinolines -- pharmacology
- Matrix Metalloproteinase 1 -- biosynthesis
- Matrix Metalloproteinase 13 -- biosynthesis
- Osteoarthritis -- enzymology
- Prostaglandin D2 -- analogs & derivatives
- Pyrroles
- RNA, Messenger -- analysis
- Receptors, Immunologic -- physiology
- Receptors, Leukotriene B4 -- agonists
- Receptors, Prostaglandin -- agonists
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Sulfonamides -- pharmacology
- Th2 Cells -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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