[A-type lamins and progeroïd syndromes : persistent farnesylation with dramatic effects]. [electronic resource]
Producer: 20090204Description: 833-40 p. digitalISSN:- 0767-0974
- Abnormalities, Multiple -- genetics
- Animals
- Cholesterol -- biosynthesis
- Disease Models, Animal
- Farnesyltranstransferase -- antagonists & inhibitors
- Humans
- Lamin Type A -- chemistry
- Male
- Membrane Proteins -- deficiency
- Metalloendopeptidases -- deficiency
- Mice
- Mice, Knockout
- Nuclear Proteins -- metabolism
- Phenotype
- Prenylation
- Progeria -- genetics
- Protein Isoforms -- genetics
- Protein Precursors -- metabolism
- Protein Processing, Post-Translational
- Protein Structure, Tertiary
- RNA Splicing
- Skin Diseases -- genetics
- Syndrome
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Publication Type: English Abstract; Journal Article; Review
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