Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1. [electronic resource]
Producer: 20090324Description: 1429-39 p. digitalISSN:- 1945-7170
- Animals
- Arteries -- drug effects
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Cells, Cultured
- Coronary Restenosis -- prevention & control
- Cyclin-Dependent Kinase Inhibitor p15 -- antagonists & inhibitors
- Cyclin-Dependent Kinase Inhibitor p27 -- antagonists & inhibitors
- Muscle, Smooth, Vascular -- drug effects
- Mutant Proteins -- chemistry
- Myocytes, Smooth Muscle -- drug effects
- Neovascularization, Physiologic -- drug effects
- Nuclear Localization Signals -- physiology
- Parathyroid Hormone-Related Protein -- chemistry
- RNA, Small Interfering -- pharmacology
- Rats
- Tunica Intima -- drug effects
- Up-Regulation -- drug effects
No physical items for this record
Publication Type: Journal Article
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