Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug. [electronic resource]
Producer: 20090217Description: 77-84 p. digitalISSN:- 1873-4995
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Administration, Oral
- Analysis of Variance
- Animals
- Area Under Curve
- Biological Availability
- Drug Delivery Systems -- methods
- Enterocytes -- metabolism
- Hypromellose Derivatives
- Immunosuppressive Agents -- chemistry
- Intestinal Absorption
- Intestinal Mucosa -- metabolism
- Intestines -- pathology
- Methylcellulose -- analogs & derivatives
- Microscopy, Electron, Scanning
- Microspheres
- Nanocapsules -- chemistry
- Particle Size
- Plant Oils -- chemistry
- Polymethacrylic Acids -- chemistry
- Rats
- Rats, Sprague-Dawley
- Surface Properties
- Swine
- Tacrolimus -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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