Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib. [electronic resource]
Producer: 20081216Description: 1722-8 p. digitalISSN:- 1521-0111
- AMP-Activated Protein Kinases -- antagonists & inhibitors
- Acetyl-CoA Carboxylase -- metabolism
- Adenosine Triphosphate -- biosynthesis
- Animals
- Animals, Newborn
- Antineoplastic Agents -- toxicity
- Apoptosis
- Cells, Cultured
- Hypoglycemic Agents -- pharmacology
- Indoles -- toxicity
- L-Lactate Dehydrogenase -- metabolism
- Metformin -- pharmacology
- Muscle Cells -- drug effects
- Oxidative Stress
- Phenformin -- pharmacology
- Phosphorylation
- Pyrroles -- toxicity
- Rats
- Rats, Sprague-Dawley
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Ribosomal Protein S6 Kinases, 90-kDa -- antagonists & inhibitors
- Sunitinib
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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