Discovery of a highly orally bioavailable c-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent. [electronic resource]
Producer: 20090424Description: 5586-90 p. digitalISSN:- 1464-3405
- Animals
- Carboxylic Acids -- chemical synthesis
- Diabetes Mellitus, Type 2 -- drug therapy
- Dioxanes -- chemical synthesis
- Humans
- Hypoglycemic Agents -- chemical synthesis
- Hypolipidemic Agents -- chemical synthesis
- Lipids -- chemistry
- Mesylates -- chemical synthesis
- Mice
- Models, Chemical
- PPAR alpha -- metabolism
- PPAR gamma -- metabolism
- Peroxisome Proliferator-Activated Receptors -- agonists
- Rats
- Rats, Wistar
- Transcriptional Activation
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Publication Type: Journal Article
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