NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens. [electronic resource]
Producer: 20090701Description: 414-23 p. digitalISSN:- 1098-1136
- Analysis of Variance
- Animals
- Animals, Newborn
- Antigens, Bacterial -- isolation & purification
- Astrocytes -- drug effects
- Borrelia burgdorferi -- pathogenicity
- Brain -- cytology
- Cell Separation
- Cells, Cultured
- Central Nervous System Bacterial Infections -- drug therapy
- Dose-Response Relationship, Drug
- Drug Synergism
- Immunoprecipitation
- Injections, Intraventricular
- Interleukin-6 -- metabolism
- Lipopolysaccharides -- pharmacology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Microglia -- drug effects
- Motor Activity
- Neisseria meningitidis -- pathogenicity
- Nod2 Signaling Adaptor Protein -- deficiency
- Oligodeoxyribonucleotides, Antisense -- therapeutic use
- Peptide Transporter 1
- Phenols
- Propionates -- pharmacology
- Receptor-Interacting Protein Serine-Threonine Kinases -- metabolism
- Symporters -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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