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  2. Details for: Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists.
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Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. [electronic resource]

By:
  • Trani, Giancarlo
Contributor(s):
  • Baddeley, Stuart M
  • Briggs, Michael A
  • Chuang, Tsu T
  • Deeks, Nigel J
  • Johnson, Christopher N
  • Khazragi, Abir A
  • Mead, Tania L
  • Medhurst, Andrew D
  • Milner, Peter H
  • Quinn, Leann P
  • Ray, Alison M
  • Rivers, Dean A
  • Stean, Tania O
  • Stemp, Geoffrey
  • Trail, Brenda K
  • Witty, David R
Producer: 20090424Description: 5698-700 p. digitalISSN:
  • 1464-3405
Subject(s):
  • Animals
  • Antidepressive Agents, Tricyclic -- chemical synthesis
  • Blood-Brain Barrier -- drug effects
  • Brain -- drug effects
  • Chemistry, Pharmaceutical -- methods
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System -- chemistry
  • Humans
  • Hydrogen Bonding
  • Microsomes -- drug effects
  • Models, Chemical
  • Molecular Conformation
  • Protein Isoforms
  • Rats
  • Receptors, Serotonin -- chemistry
  • Serotonin Antagonists -- chemical synthesis
Online resources:
  • Available from publisher's website
In: Bioorganic & medicinal chemistry letters vol. 18
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Publication Type: Journal Article

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Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists.

APA

Trani G., Baddeley S. M., Briggs M. A., Chuang T. T., Deeks N. J., Johnson C. N., Khazragi A. A., Mead T. L., Medhurst A. D., Milner P. H., Quinn L. P., Ray A. M., Rivers D. A., Stean T. O., Stemp G., Trail B. K. & Witty D. R. (20090424). Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. : Bioorganic & medicinal chemistry letters.

Chicago

Trani Giancarlo, Baddeley Stuart M, Briggs Michael A, Chuang Tsu T, Deeks Nigel J, Johnson Christopher N, Khazragi Abir A, Mead Tania L, Medhurst Andrew D, Milner Peter H, Quinn Leann P, Ray Alison M, Rivers Dean A, Stean Tania O, Stemp Geoffrey, Trail Brenda K and Witty David R. 20090424. Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. : Bioorganic & medicinal chemistry letters.

Harvard

Trani G., Baddeley S. M., Briggs M. A., Chuang T. T., Deeks N. J., Johnson C. N., Khazragi A. A., Mead T. L., Medhurst A. D., Milner P. H., Quinn L. P., Ray A. M., Rivers D. A., Stean T. O., Stemp G., Trail B. K. and Witty D. R. (20090424). Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. : Bioorganic & medicinal chemistry letters.

MLA

Trani Giancarlo, Baddeley Stuart M, Briggs Michael A, Chuang Tsu T, Deeks Nigel J, Johnson Christopher N, Khazragi Abir A, Mead Tania L, Medhurst Andrew D, Milner Peter H, Quinn Leann P, Ray Alison M, Rivers Dean A, Stean Tania O, Stemp Geoffrey, Trail Brenda K and Witty David R. Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. : Bioorganic & medicinal chemistry letters. 20090424.

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