Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists. [electronic resource]
Producer: 20090424Description: 5698-700 p. digitalISSN:- 1464-3405
- Animals
- Antidepressive Agents, Tricyclic -- chemical synthesis
- Blood-Brain Barrier -- drug effects
- Brain -- drug effects
- Chemistry, Pharmaceutical -- methods
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- chemistry
- Humans
- Hydrogen Bonding
- Microsomes -- drug effects
- Models, Chemical
- Molecular Conformation
- Protein Isoforms
- Rats
- Receptors, Serotonin -- chemistry
- Serotonin Antagonists -- chemical synthesis
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Publication Type: Journal Article
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