Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site. [electronic resource]
Producer: 20100331Description: 2754-63 p. digitalISSN:- 1529-0131
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Blotting, Western
- Bone Morphogenetic Protein 6 -- pharmacology
- Carbamates -- pharmacology
- Cell Cycle Proteins -- genetics
- Cell Differentiation -- physiology
- Cells, Cultured
- Chondrogenesis -- drug effects
- Chromatin Immunoprecipitation
- Collagen Type II -- metabolism
- Dipeptides -- pharmacology
- Fibroblast Growth Factor 2 -- pharmacology
- Homeodomain Proteins -- genetics
- Humans
- Mesenchymal Stem Cells
- Receptors, Notch -- genetics
- Regulatory Sequences, Nucleic Acid -- genetics
- Repressor Proteins -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Time Factors
- Transcription Factor HES-1
- Transforming Growth Factor beta3 -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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