Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome. [electronic resource]
Producer: 20100713Description: 953-68 p. digitalISSN:- 1558-1497
- Alanine -- genetics
- Ammonium Chloride -- pharmacology
- Animals
- Benzoquinones -- pharmacology
- Cerebral Cortex -- drug effects
- Chromatography, Gel -- methods
- Coloring Agents -- pharmacology
- Congo Red -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Enzymologic -- drug effects
- Green Fluorescent Proteins -- genetics
- Humans
- Immunoprecipitation -- methods
- Lactams, Macrocyclic -- pharmacology
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation -- genetics
- PC12 Cells -- metabolism
- Proteasome Endopeptidase Complex -- metabolism
- Protein Folding
- Rats
- Transfection -- methods
- Tyrosine -- genetics
- alpha-Synuclein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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