Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase. [electronic resource]
Producer: 20081231Description: 814-23 p. digitalISSN:- 1097-4644
- AMP-Activated Protein Kinases -- metabolism
- Animals
- Cells, Cultured
- Elongation Factor 2 Kinase -- metabolism
- HIV Protease Inhibitors -- pharmacology
- Lopinavir
- Mice
- Peptide Elongation Factor 2 -- antagonists & inhibitors
- Phosphorylation
- Protein Biosynthesis -- drug effects
- Pyrimidinones -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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