Tumour necrosis factor (TNF)-alpha primes murine neutrophils when triggered via formyl peptide receptor-related sequence 2, the murine orthologue of human formyl peptide receptor-like 1, through a process involving the type I TNF receptor and subcellular granule mobilization. [electronic resource]
Producer: 20090220Description: 591-600 p. digitalISSN:- 1365-2567
- Animals
- Biomarkers -- analysis
- Cells, Cultured
- Chemotaxis, Leukocyte
- Cytoplasmic Granules -- physiology
- Electroporation
- Female
- HL-60 Cells
- Humans
- Macrophage-1 Antigen -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Neutrophil Activation
- Neutrophils -- drug effects
- Oligopeptides -- metabolism
- Reactive Oxygen Species -- analysis
- Receptors, Formyl Peptide -- genetics
- Receptors, Tumor Necrosis Factor, Type I -- genetics
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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