hMTH1 depletion promotes oxidative-stress-induced apoptosis through a Noxa- and caspase-3/7-mediated signaling pathway. [electronic resource]
Producer: 20081229Description: 1809-23 p. digitalISSN:- 1568-7864
- Apoptosis
- Caspase 3 -- metabolism
- Caspase 7 -- metabolism
- Cell Line, Tumor
- Comet Assay
- DNA Repair Enzymes -- metabolism
- Humans
- Hydrogen Peroxide -- pharmacology
- Models, Biological
- Oxidative Stress
- Phosphoric Monoester Hydrolases -- metabolism
- Phosphorylation
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Signal Transduction
- Time Factors
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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