5-(4-Chlorophenyl)-5,6-dihydro-1,3-oxazepin-7(4H)-one derivatives as lipophilic cyclic analogues of baclofen: design, synthesis, and neuropharmacological evaluation. [electronic resource]
Producer: 20081103Description: 7983-91 p. digitalISSN:- 1464-3391
- Animals
- Baclofen -- chemistry
- Cognition Disorders -- drug therapy
- Cyclization
- Dose-Response Relationship, Drug
- Drug Design
- Drug Evaluation, Preclinical
- GABA Agonists -- chemical synthesis
- GABA-B Receptor Agonists
- Hydrophobic and Hydrophilic Interactions
- Injections, Intraperitoneal
- Magnetic Resonance Spectroscopy -- methods
- Male
- Mice
- Molecular Structure
- Motor Activity -- drug effects
- Muscle Relaxation -- drug effects
- Oxazepines -- chemical synthesis
- Pain -- drug therapy
- Receptors, GABA-B -- chemistry
- Reference Standards
- Stereoisomerism
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Publication Type: Journal Article
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