Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. [electronic resource]
Producer: 20080814Description: 3709-14 p. digitalISSN:- 1527-7755
- Administration, Oral
- Adult
- Aged
- Angiogenesis Inhibitors -- administration & dosage
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Humanized
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Benzenesulfonates -- administration & dosage
- Bevacizumab
- Drug Administration Schedule
- Female
- Humans
- Male
- Maximum Tolerated Dose
- Middle Aged
- Neoplasm Staging
- Neoplasms -- drug therapy
- Niacinamide -- analogs & derivatives
- Ovarian Neoplasms -- drug therapy
- Phenylurea Compounds
- Protein Kinase Inhibitors -- administration & dosage
- Pyridines -- administration & dosage
- Receptors, Vascular Endothelial Growth Factor -- antagonists & inhibitors
- Sorafenib
- Treatment Outcome
- Vascular Endothelial Growth Factor A -- antagonists & inhibitors
- raf Kinases -- antagonists & inhibitors
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Intramural
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