Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors. [electronic resource]
Producer: 20081003Description: 513-24 p. digitalISSN:- 0340-5761
- 20-Hydroxysteroid Dehydrogenases -- genetics
- Aged
- Cadmium Compounds -- toxicity
- Cell Cycle -- drug effects
- Cells, Cultured
- Cobalt -- toxicity
- DNA Damage
- Dose-Response Relationship, Drug
- Epithelial Cells -- drug effects
- Female
- Gene Expression Regulation -- drug effects
- Humans
- Hydroxysteroid Dehydrogenases -- genetics
- Lead -- toxicity
- Male
- Middle Aged
- Occupational Exposure -- adverse effects
- Oligonucleotide Array Sequence Analysis
- Oxidative Stress -- drug effects
- Respiratory Mucosa -- drug effects
- Steroids -- metabolism
- Sulfates -- toxicity
- Transcription Factors -- metabolism
- Transcription, Genetic -- drug effects
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Publication Type: Journal Article
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