Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats. [electronic resource]
Producer: 20081118Description: 1572-9 p. digitalISSN:- 1525-0024
- Amphetamine -- pharmacology
- Animals
- Behavior, Animal
- Brain -- drug effects
- Cell Nucleus -- metabolism
- Cells, Cultured
- Cytoplasm -- metabolism
- Dependovirus -- genetics
- Female
- Forelimb -- drug effects
- Genes, Dominant -- physiology
- Genetic Therapy
- Genetic Vectors
- Green Fluorescent Proteins -- metabolism
- Immunoenzyme Techniques
- Male
- Nerve Degeneration -- genetics
- Neurons -- metabolism
- Oxidopamine -- pharmacology
- Parkinson Disease -- genetics
- Protein Transport
- Rats
- Rats, Inbred F344
- Rats, Sprague-Dawley
- Substantia Nigra -- metabolism
- Transcription Factor RelA -- metabolism
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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