Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells. [electronic resource]
Producer: 20080829Description: 127-33 p. digitalISSN:- 0340-6245
- Breast Neoplasms -- enzymology
- Cell Line, Tumor
- Cell Movement -- drug effects
- Chromones -- pharmacology
- Factor VIIa -- metabolism
- Factor Xa -- metabolism
- Female
- Humans
- Morpholines -- pharmacology
- Neoplasm Invasiveness
- Peptides -- pharmacology
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- drug effects
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Receptor, PAR-1 -- metabolism
- Receptor, PAR-2 -- metabolism
- Recombinant Proteins -- metabolism
- Ribosomal Protein S6 Kinases, 70-kDa -- metabolism
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases
- Thromboplastin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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