Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease. [electronic resource]
Producer: 20081021Description: 3617-27 p. digitalISSN:- 1530-6860
- Animals
- Apoptosis -- drug effects
- Benzamides
- Cell Survival -- drug effects
- Cerebellar Cortex -- drug effects
- DNA-Binding Proteins -- metabolism
- Disease Models, Animal
- Gene Expression -- drug effects
- Imatinib Mesylate
- Intracellular Signaling Peptides and Proteins
- Mice
- Mice, Knockout
- Motor Activity -- drug effects
- Niemann-Pick C1 Protein
- Niemann-Pick Disease, Type C -- drug therapy
- Nuclear Proteins -- metabolism
- Piperazines -- therapeutic use
- Proteins -- genetics
- Proto-Oncogene Proteins c-abl -- metabolism
- Purkinje Cells -- drug effects
- Pyrimidines -- therapeutic use
- RNA, Messenger -- antagonists & inhibitors
- Tumor Protein p73
- Tumor Suppressor Proteins -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.