Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor beta (TR-beta) selective ligands. [electronic resource]
Producer: 20081117Description: 3919-24 p. digitalISSN:- 1464-3405
- Chemistry, Pharmaceutical -- methods
- Crystallography, X-Ray
- Cyclobutanes -- chemistry
- Drug Design
- Humans
- Ligands
- Luciferases -- metabolism
- Models, Chemical
- Molecular Conformation
- Phenyl Ethers -- pharmacology
- Phenylacetates -- pharmacology
- Protein Binding
- Structure-Activity Relationship
- Thyroid Gland -- enzymology
- Thyroid Hormone Receptors alpha -- metabolism
- Thyroid Hormone Receptors beta -- chemistry
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Publication Type: Journal Article
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