PKC gamma mutations in spinocerebellar ataxia type 14 affect C1 domain accessibility and kinase activity leading to aberrant MAPK signaling. [electronic resource]
Producer: 20081007Description: 2339-49 p. digitalISSN:- 0021-9533
- Amino Acid Sequence
- Cell Membrane -- drug effects
- Cell Nucleus -- drug effects
- Cell Survival -- drug effects
- Enzyme Activation -- drug effects
- HeLa Cells
- Humans
- Kinetics
- MAP Kinase Signaling System -- drug effects
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Molecular Sequence Data
- Mutation -- genetics
- Protein Kinase C -- chemistry
- Protein Structure, Tertiary
- Protein Transport -- drug effects
- Spinocerebellar Ataxias -- enzymology
- Subcellular Fractions -- drug effects
- Tetradecanoylphorbol Acetate -- pharmacology
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Publication Type: Journal Article
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