R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin. [electronic resource]
Producer: 20080905Description: 385-97 p. digitalISSN:- 1527-3350
- Adult
- Aged
- Aged, 80 and over
- Alanine Transaminase -- blood
- Antiviral Agents -- administration & dosage
- Cytidine -- analogs & derivatives
- Dose-Response Relationship, Drug
- Double-Blind Method
- Drug Resistance, Viral
- Drug Synergism
- Drug Therapy, Combination
- Female
- Hepacivirus -- enzymology
- Humans
- Interferon alpha-2
- Interferon-alpha -- adverse effects
- Male
- Middle Aged
- Neutropenia -- chemically induced
- Nucleosides -- administration & dosage
- Polyethylene Glycols -- adverse effects
- Prodrugs -- administration & dosage
- RNA, Viral -- antagonists & inhibitors
- Recombinant Proteins
- Ribavirin -- adverse effects
- Treatment Outcome
- Viral Load
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
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