Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. [electronic resource]
Producer: 20080925Description: 2562-73 p. digitalISSN:- 0021-9738
- Animals
- Antigens, CD -- metabolism
- Bone Marrow Transplantation
- Cytokines -- metabolism
- Dendritic Cells -- drug effects
- Enzyme Inhibitors -- pharmacology
- Female
- Gene Expression -- drug effects
- Graft vs Host Disease -- pathology
- Histone Deacetylase Inhibitors
- Humans
- Hydroxamic Acids -- pharmacology
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- genetics
- Lipopolysaccharides -- pharmacology
- Lymphocyte Activation -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mice, Knockout
- RNA, Small Interfering -- genetics
- Survival Analysis
- T-Lymphocytes -- drug effects
- Vorinostat
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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