PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells. [electronic resource]
Producer: 20080819Description: 1407-14 p. digitalISSN:- 1460-2180
- Apoptosis -- drug effects
- Caco-2 Cells
- Caspase 3 -- biosynthesis
- Caspase 8 -- biosynthesis
- Cell Cycle -- drug effects
- Cell Growth Processes -- drug effects
- Colonic Neoplasms -- drug therapy
- Down-Regulation -- drug effects
- HCT116 Cells
- HT29 Cells
- Humans
- Inhibitor of Apoptosis Proteins -- biosynthesis
- Mesalamine -- pharmacology
- PPAR gamma -- biosynthesis
- PTEN Phosphohydrolase -- biosynthesis
- Proto-Oncogene Proteins c-myc -- biosynthesis
- Signal Transduction
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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