Inhibition of invariant chain processing, antigen-induced proliferative responses, and the development of collagen-induced arthritis and experimental autoimmune encephalomyelitis by a small molecule cysteine protease inhibitor. [electronic resource]
Producer: 20080905Description: 7989-8003 p. digitalISSN:- 0022-1767
- Animals
- Antigens, Differentiation, B-Lymphocyte -- metabolism
- Arthritis, Experimental -- enzymology
- Azepines -- administration & dosage
- Benzofurans -- administration & dosage
- Cathepsins -- antagonists & inhibitors
- Cattle
- Cell Line, Tumor
- Cells, Cultured
- Collagen Type II -- immunology
- Cysteine Proteinase Inhibitors -- administration & dosage
- Encephalomyelitis, Autoimmune, Experimental -- enzymology
- Female
- Histocompatibility Antigens Class II -- metabolism
- Humans
- Leucine -- administration & dosage
- Lymphocyte Activation -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Knockout
- Protein Processing, Post-Translational -- drug effects
- Pyridines -- administration & dosage
- Spleen -- cytology
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Publication Type: Journal Article
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