Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor. [electronic resource]
Producer: 20080926Description: 1594-605 p. digitalISSN:- 1521-009X
- Acetaminophen -- metabolism
- Alkaloids -- pharmacology
- Benzodioxoles -- pharmacology
- Chromatography, High Pressure Liquid
- Curcumin -- pharmacology
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors -- pharmacology
- Glucuronosyltransferase -- antagonists & inhibitors
- Humans
- Liver -- drug effects
- Piperidines -- pharmacology
- Polyunsaturated Alkamides -- pharmacology
- Recombinant Proteins -- antagonists & inhibitors
- Spectrometry, Fluorescence
- Spectrometry, Mass, Electrospray Ionization
- Spectrophotometry, Ultraviolet
- Sulfotransferases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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