Inhalable large porous microspheres of low molecular weight heparin: in vitro and in vivo evaluation. [electronic resource]
Producer: 20080813Description: 224-32 p. digitalISSN:- 1873-4995
- Administration, Inhalation
- Amines -- chemistry
- Animals
- Anticoagulants -- administration & dosage
- Cell Line
- Cell Survival -- drug effects
- Chemistry, Pharmaceutical
- Dose-Response Relationship, Drug
- Drug Carriers
- Drug Compounding
- Factor Xa Inhibitors
- Feasibility Studies
- Glycolates -- chemistry
- Heparin, Low-Molecular-Weight -- administration & dosage
- Hexoses -- chemistry
- Humans
- Kinetics
- Lactic Acid
- Lung -- metabolism
- Male
- Microspheres
- Particle Size
- Polyethyleneimine -- chemistry
- Polyglycolic Acid
- Polylactic Acid-Polyglycolic Acid Copolymer
- Porosity
- Powders
- Rats
- Rats, Sprague-Dawley
- Solubility
- Surface Properties
- Technology, Pharmaceutical -- methods
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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