Synthesis and structure based optimization of novel Akt inhibitors. [electronic resource]
Producer: 20080709Description: 3359-63 p. digitalISSN:- 1464-3405
- Animals
- Antineoplastic Agents -- chemical synthesis
- Combinatorial Chemistry Techniques
- Crystallography, X-Ray
- Disease Models, Animal
- Drug Design
- Inhibitory Concentration 50
- Mice
- Molecular Conformation
- Molecular Structure
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Pyrimidines -- chemical synthesis
- Pyrroles -- chemical synthesis
- Spiro Compounds -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article
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