The effect of azacitidine on interleukin-6 signaling and nuclear factor-kappaB activation and its in vitro and in vivo activity against multiple myeloma. [electronic resource]
Producer: 20080912Description: 860-9 p. digitalISSN:- 1592-8721
- Active Transport, Cell Nucleus
- Antimetabolites, Antineoplastic -- pharmacology
- Apoptosis
- Azacitidine -- pharmacology
- Cell Line, Tumor
- Gene Expression Regulation, Neoplastic
- Humans
- In Vitro Techniques
- Interleukin-6 -- metabolism
- Multiple Myeloma -- drug therapy
- NF-kappa B -- metabolism
- Phosphorylation
- STAT3 Transcription Factor -- metabolism
- Signal Transduction
- Tetrazolium Salts -- pharmacology
- bcl-X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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