Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide. [electronic resource]
Producer: 20081105Description: 1424-31 p. digitalISSN:- 1522-9645
- Adult
- Child
- Drug-Related Side Effects and Adverse Reactions
- Epidemiologic Methods
- Female
- Genetic Predisposition to Disease
- Genotype
- Heart Defects, Congenital -- enzymology
- Humans
- Hyperhomocysteinemia -- genetics
- Male
- Niacinamide -- administration & dosage
- Nicotinamide N-Methyltransferase -- genetics
- Polymorphism, Single Nucleotide
- Pregnancy
- Prenatal Exposure Delayed Effects
- Vitamin B Complex -- administration & dosage
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Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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