Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency. [electronic resource]
Producer: 20081202Description: 448-57 p. digitalISSN:- 0008-6363
- Adrenal Glands -- abnormalities
- Animals
- Body Patterning
- Gene Expression Regulation, Developmental
- Germ Layers -- metabolism
- Gestational Age
- Heart -- embryology
- Heart Defects, Congenital -- embryology
- Heterozygote
- Homeodomain Proteins -- genetics
- Magnetic Resonance Imaging
- Mesoderm -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Myocardium -- metabolism
- Neural Crest -- metabolism
- Organogenesis
- Phenotype
- Polymerase Chain Reaction
- Recombination, Genetic
- Repressor Proteins -- genetics
- Trans-Activators -- deficiency
- Transcription Factors -- genetics
- Homeobox Protein PITX2
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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