Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. [electronic resource]
Producer: 20080528Description: e1981 p. digitalISSN:- 1932-6203
- Adrenergic alpha-2 Receptor Agonists
- Animals
- Antihypertensive Agents -- pharmacology
- Disease Models, Animal
- Guanabenz -- analogs & derivatives
- Injections, Intraperitoneal
- Mice
- Mice, Transgenic
- PrPSc Proteins -- chemistry
- Prion Diseases -- drug therapy
- Prions -- drug effects
- Protein Structure, Quaternary
- Saccharomyces cerevisiae -- drug effects
- Sheep
- Spleen -- drug effects
- Survival Rate
- Tacrine -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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