Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. [electronic resource]
Producer: 20080513Description: 425-35 p. digitalISSN:- 1097-4180
- Animals
- Antigen Presentation -- immunology
- Antigen-Presenting Cells -- immunology
- B7-1 Antigen -- immunology
- CD28 Antigens -- immunology
- CD4-Positive T-Lymphocytes -- cytology
- CD40 Antigens -- immunology
- CD40 Ligand -- immunology
- Cell Differentiation -- immunology
- Cell Survival -- immunology
- Complement C3a -- immunology
- Complement C5a -- immunology
- Flow Cytometry
- Immunoblotting
- Immunoprecipitation
- Lymphocyte Activation -- immunology
- Mice
- Mice, Transgenic
- Polymerase Chain Reaction
- RNA, Messenger -- analysis
- Receptor, Anaphylatoxin C5a -- immunology
- Signal Transduction -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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