Benzyl ether-linked glucuronide derivative of 10-hydroxycamptothecin designed for selective camptothecin-based anticancer therapy. [electronic resource]
Producer: 20080611Description: 1740-6 p. digitalISSN:- 0022-2623
- Antibodies, Neoplasm -- chemistry
- Antineoplastic Agents -- chemistry
- Binding, Competitive
- Camptothecin -- analogs & derivatives
- Catalysis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Design
- Drug Screening Assays, Antitumor
- Escherichia coli -- enzymology
- Glucuronidase -- chemistry
- Glucuronides -- chemistry
- Humans
- Kinetics
- Models, Molecular
- Molecular Structure
- Neoplasms -- drug therapy
- Phenyl Ethers -- chemistry
- Prodrugs -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article
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