Eif-2a protects brainstem motoneurons in a murine model of sleep apnea. [electronic resource]
Producer: 20080408Description: 2168-78 p. digitalISSN:- 1529-2401
- Animals
- Brain Stem -- pathology
- Caspases -- metabolism
- Choline O-Acetyltransferase -- metabolism
- Cinnamates -- pharmacology
- Disease Models, Animal
- Endoplasmic Reticulum
- Eukaryotic Initiation Factor-2 -- metabolism
- Gene Expression Regulation
- Hypoxia -- complications
- Male
- Mice
- Mice, Inbred C57BL
- Microscopy, Electron, Transmission -- methods
- Motor Neurons -- metabolism
- Oxidative Stress
- Phosphorylation -- drug effects
- Sleep Apnea Syndromes -- etiology
- Thiourea -- analogs & derivatives
- Transcription Factor CHOP -- metabolism
- eIF-2 Kinase -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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