Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin. [electronic resource]
Producer: 20080416Description: 117-24 p. digitalISSN:- 1556-1380
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Biomarkers, Tumor -- blood
- Cadherins -- blood
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Celecoxib
- Chemokines, CC -- blood
- Cyclooxygenase Inhibitors -- pharmacology
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm
- ErbB Receptors -- antagonists & inhibitors
- Erlotinib Hydrochloride
- Humans
- Lung Neoplasms -- drug therapy
- Macrophage Inflammatory Proteins -- blood
- Matrix Metalloproteinase 9 -- blood
- Protein Kinase Inhibitors -- pharmacology
- Pyrazoles -- administration & dosage
- Quinazolines -- administration & dosage
- Sulfonamides -- administration & dosage
- Tissue Inhibitor of Metalloproteinase-1 -- blood
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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