High tidal volume ventilation activates Smad2 and upregulates expression of connective tissue growth factor in newborn rat lung. [electronic resource]
Producer: 20080328Description: 245-50 p. digitalISSN:- 0031-3998
- Animals
- Animals, Newborn
- Connective Tissue Growth Factor
- Immediate-Early Proteins -- genetics
- Intercellular Signaling Peptides and Proteins -- genetics
- Interleukin-6 -- genetics
- Lung -- growth & development
- Lung Diseases -- etiology
- Phosphorylation
- Positive-Pressure Respiration -- adverse effects
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Signal Transduction
- Smad2 Protein -- metabolism
- Smad7 Protein -- metabolism
- Tidal Volume
- Time Factors
- Transforming Growth Factor beta -- metabolism
- Tumor Necrosis Factor-alpha
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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