Non-invasive method to detect induction of CYP3A4 in chimeric mice with a humanized liver. [electronic resource]
Producer: 20081003Description: 239-48 p. digitalISSN:- 0049-8254
- Animals
- Biological Assay -- methods
- Chimera -- metabolism
- Chromatography
- Cytochrome P-450 CYP3A -- biosynthesis
- Dexamethasone -- administration & dosage
- Enzyme Induction -- drug effects
- Humans
- Immunohistochemistry
- Kinetics
- Liver -- drug effects
- Mice
- Microsomes, Liver -- drug effects
- Recombinant Proteins -- metabolism
- Rifampin -- pharmacology
- Substrate Specificity -- drug effects
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Publication Type: Journal Article
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