NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation. [electronic resource]
Producer: 20090401Description: S316-20 p. digitalISSN:- 1353-8020
- Analysis of Variance
- Animals
- Biphenyl Compounds -- pharmacology
- Brain -- cytology
- Cells, Cultured
- Dopamine -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Female
- Microglia -- drug effects
- NADPH Oxidases -- antagonists & inhibitors
- Neurons -- cytology
- Neuroprotective Agents -- pharmacology
- Nitrites -- metabolism
- Onium Compounds -- pharmacology
- Pregnancy
- Rats
- Rats, Inbred F344
- Reactive Oxygen Species -- metabolism
- Superoxides -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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