Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2. [electronic resource]
Producer: 20080522Description: 9177-86 p. digitalISSN:- 0021-9258
- Amino Acid Motifs -- genetics
- Animals
- CSK Tyrosine-Protein Kinase
- Cell Line
- Disease Models, Animal
- Extracellular Signal-Regulated MAP Kinases -- genetics
- GRB2 Adaptor Protein -- genetics
- Humans
- Kidney Diseases -- genetics
- MAP Kinase Signaling System -- genetics
- Male
- Membrane Proteins -- genetics
- Peptide Mapping -- methods
- Peptides -- genetics
- Phosphorylation
- Podocytes -- metabolism
- Protein-Tyrosine Kinases -- genetics
- Proto-Oncogene Proteins c-fyn -- genetics
- Rats
- Rats, Wistar
- TRPC Cation Channels -- genetics
- TRPC6 Cation Channel
- src Homology Domains -- genetics
- src-Family Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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