Double-stranded RNA mediates interferon regulatory factor 3 activation and interleukin-6 production by engaging Toll-like receptor 3 in human brain astrocytes. [electronic resource]
Producer: 20081204Description: 480-8 p. digitalISSN:- 1365-2567
- Astrocytes -- immunology
- Brain -- embryology
- Cells, Cultured
- Dose-Response Relationship, Immunologic
- Electrophoretic Mobility Shift Assay -- methods
- Fetus -- immunology
- Humans
- I-kappa B Proteins -- metabolism
- Interferon Regulatory Factor-3 -- metabolism
- Interferon-gamma -- immunology
- Interleukin-6 -- biosynthesis
- Mitogen-Activated Protein Kinase Kinases -- immunology
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Polynucleotides -- immunology
- RNA, Double-Stranded -- immunology
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- STAT1 Transcription Factor -- metabolism
- Toll-Like Receptor 3 -- metabolism
- Up-Regulation -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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