SIK2 can be activated by deprivation of nutrition and it inhibits expression of lipogenic genes in adipocytes. [electronic resource]
Producer: 20080522Description: 531-8 p. digitalISSN:- 1930-7381
- 3T3-L1 Cells
- AMP-Activated Protein Kinases
- Acetyl-CoA Carboxylase -- genetics
- Adenosine Triphosphate -- metabolism
- Adipocytes -- drug effects
- Aminoimidazole Carboxamide -- pharmacology
- Animals
- Dose-Response Relationship, Drug
- Down-Regulation
- Electroporation
- Enzyme Activation
- Enzyme Activators -- pharmacology
- Fatty Acid Synthases -- genetics
- Gene Expression Regulation, Enzymologic -- drug effects
- Genes, Reporter
- Glucose -- deficiency
- Lipogenesis -- drug effects
- Mice
- Multienzyme Complexes -- metabolism
- Phosphorylation
- Promoter Regions, Genetic
- Protein Serine-Threonine Kinases -- genetics
- RNA Interference
- RNA, Small Interfering -- metabolism
- Stearoyl-CoA Desaturase -- genetics
- Sterol Regulatory Element Binding Protein 1 -- metabolism
- Time Factors
- Transfection
- Triglycerides -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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