Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death. [electronic resource]
Producer: 20080414Description: 284-98 p. digitalISSN:- 0891-5849
- Bilirubin -- pharmacology
- Biliverdine -- pharmacology
- Carbon Monoxide -- metabolism
- Cell Death -- drug effects
- Endothelium, Vascular -- cytology
- Heart
- Heme Oxygenase-1 -- genetics
- Hemin -- pharmacology
- Humans
- Interleukin-18 -- antagonists & inhibitors
- NF-kappa B -- metabolism
- Organometallic Compounds -- pharmacology
- PTEN Phosphohydrolase -- metabolism
- Protein Isoforms -- antagonists & inhibitors
- Protoporphyrins -- pharmacology
- RNA, Small Interfering -- pharmacology
- Transcription, Genetic -- drug effects
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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