Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4. [electronic resource]
Producer: 20080613Description: 762-72 p. digitalISSN:- 1350-9047
- Adult
- Aged
- Antibodies, Monoclonal
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Autocrine Communication
- Breast Neoplasms -- drug therapy
- CASP8 and FADD-Like Apoptosis Regulating Protein -- metabolism
- Carcinoma -- drug therapy
- Cell Death
- Cell Proliferation
- Colonic Neoplasms -- drug therapy
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm
- Female
- Humans
- Interleukin-4 -- immunology
- Interleukin-4 Receptor alpha Subunit -- metabolism
- Intracellular Signaling Peptides and Proteins -- metabolism
- Lung Neoplasms -- drug therapy
- Male
- Middle Aged
- Phosphoproteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Signal Transduction
- TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Time Factors
- Tumor Cells, Cultured
- Up-Regulation
- bcl-X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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