NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts. [electronic resource]
Producer: 20080221Description: 81-8 p. digitalISSN:- 1551-4005
- Animals
- Aspirin -- analogs & derivatives
- Cell Line, Tumor
- Cisplatin -- pharmacology
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- drug effects
- ErbB Receptors -- antagonists & inhibitors
- Female
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Ovarian Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- STAT3 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Transplantation, Heterologous -- pathology
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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